Role of Perilesional Sampling of Patients Undergoing Fusion Prostate Biopsies

Recently, researchers have proposed perilesional sampling during prostate biopsies to avoid systematic of patients at risk cancer. The aim our study is evaluate the role undergoing fusion biopsies. A prospective cohort transrectal MRI were consecutively enrolled. All underwent (SB), targeted (TB) and within 10 mm from lesion (PB). detection rates different strategies determined. total 262 median age those enrolled was 70 years. mean BMI 27 kg/m2, volume 52 mL. PIRADS score ≥ 4 recorded in 163/262 (40%) patients. Overall, cancer 43.5% (114/262) 35% (92/262) for csPCa. use target + peri-target strategy resulted a 32.8% (86/262) cases 29% (76/262) csPCa (Grade Group > 2). Using plus approach us missing 18/262 (7%) cases, avoiding diagnosis 8/262 (3%) nsPCa cases. biopsy including lesional could unnecessary However, significant cancers present. Future studies should assess cost–benefit relationship strategies.